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[Electron microscopic study of the reticulated cellular structures induced in Lepidoptera by baculovirus]
Comptes Rendus Hebdomadaires Des Seances De L'Academie Des Sciences. Serie D: Sciences Naturelles
|October 6, 1975
Abstract:
Five of six Baculovirus species studied induce cytoplasmic and nuclear fibrous sheets, observed by electron microscopy, within infected cells of lepidopterous. The reticulated structures, revealed by fluorescence microscopy, assimilate the fibrillar substance induced by these viruses thanks to the affinity they show for globulins of healthy rabbits.
Insights
Baculoviruses can create fibrous sheets in insect cells, forming structures that bind to rabbit proteins. This viral-induced material is found in both the cytoplasm and nucleus of infected lepidopteran cells.
Area of Science:
- Virology
- Cell Biology
- Microscopy
Context:
- Baculoviruses are significant pathogens of insects, particularly Lepidoptera.
- Viral-induced cellular changes are crucial for understanding infection dynamics.
- Electron and fluorescence microscopy are key techniques for visualizing cellular structures.
Purpose:
- To investigate the formation and characteristics of fibrous sheets induced by Baculovirus species.
- To analyze the cellular localization and composition of these viral-induced structures.
- To explore the interaction of these structures with host and foreign proteins.
Summary:
- Five of six studied Baculovirus species induce fibrous sheets in the cytoplasm and nucleus of infected lepidopteran cells.
- Reticulated structures within these cells assimilate the fibrillar viral substance.
- These structures exhibit an affinity for globulins from healthy rabbits, suggesting specific binding properties.
Impact:
- Provides insights into the physical alterations of host cells during Baculovirus infection.
- Highlights the potential for viral-induced materials to interact with host or exogenous proteins.
- Contributes to the understanding of viral morphogenesis and cellular manipulation.