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Developmental odontogenic cysts. An update

M Shear1

  • 1Department of Oral Pathology, University of the Witwatersrand, Johannesburg, South Africa.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
|January 1, 1994
PubMed
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This review covers recent advances in developmental odontogenic cysts, focusing on the latest WHO classification. It assesses keratocysts, dentigerous cysts, and related lesions, offering insights into their behavior and relationships.

Area of Science:

  • Dentistry
  • Oral Pathology
  • Oncology

Background:

  • Developmental odontogenic cysts represent a group of jaw pathologies with varying clinical and histological features.
  • Recent advancements necessitate an updated understanding of their classification and behavior.

Purpose of the Study:

  • To review recent advances in developmental odontogenic cysts over the past decade.
  • To critically analyze the latest WHO classification and its implications.
  • To explore the immunobiology, genetics, and behavior of specific cyst types.

Main Methods:

  • Literature review of recent studies (past decade) on odontogenic cysts.
  • Analysis of data on recurrence rates, growth patterns, and immunocytochemistry.
  • Critical assessment of classifications and relationships between different cyst entities.

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Main Results:

  • Updated insights into keratocysts, including recurrence rates and genetic factors.
  • Clarification of the relationships among gingival cysts, lateral periodontal cysts, and glandular odontogenic cysts.
  • Review of dentigerous cysts, unicystic ameloblastomas, and calcifying odontogenic cysts.

Conclusions:

  • The review provides a contemporary overview of odontogenic cyst advancements.
  • It highlights the importance of the new WHO classification for accurate diagnosis and management.
  • Further research into the specific antigens and genetic underpinnings of these lesions is suggested.