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[Therapy of simple endometrial hyperplasia with GnRH analogs. Evaluation of a multicentric ambulatory study.
R Zagni1, R Cortelazzi, L Cipolla
1Divisione di Ostetricia e Ginecologia, Ospedale Generale di Zona-Chiavenna, Sondrio.
Minerva Ginecologica
|December 1, 1993
Abstract:
Endometrial hyperplasia is a frequent pathology during menopause and involves the risk of malignant transformation of the lesions. In an attempt to avoid radical surgery, this study proposes the use of triptorelin which was used to treat 56 patients with histologically confirmed symptoms of endometrial hyperplasia without atypia. GnRH-analog was administered using the intramuscular route every 28 days for 6 months. Histological controls were carried out 30 days after the last injection and showed the resolution of histological symptoms, confirmed after three months.