Related Experiment Videos
[Evaluation of drug side effects over a year in a cardiology service]
M Jamaa1, P Laine-Cessac, J Victor
1Service de cardiologie, C.H.R.U., Angers.
Insights
A year-long cardiology study found 2.3% of hospitalized patients experienced adverse drug reactions, primarily elderly females. Cardiovascular and hemorrhagic events were most common, often linked to cardiovascular medications.
Area of Science:
- Pharmacology
- Clinical Cardiology
- Drug Safety
Abstract:
An intensive pharmacovigilance survey was carried out over the course of 1 year in cardiology department which revealed 64 reports of adverse drug reactions among 61 hospitalised patients, giving an overall incidence of 2.3%. Most of the patients in whom adverse drug reactions were recorded were elderly and female. The most common adverse events were cardiovascular (72%) and haemorrhagic (9%), and related to drugs given for the treatment of cardiovascular disorders. The symptoms originating from drug therapy were dominated by sinus arrhythmias (25 cases), linked to drugs co-administered that have potentially similar cardiac pharmacodynamic effects. Seven cases of "torsades de pointe" were also observed.