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Molecular imprinting

K Mosbach1

  • 1Department of Pure and Applied Biochemistry, University of Lund, Sweden.

Trends in Biochemical Sciences
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Molecular imprinting creates selective synthetic polymers by polymerizing functional monomers with a template molecule. These polymers show high stereo- and regiospecific selectivity for applications like chiral separations and antibody mimics.

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Area of Science:

  • Polymer Chemistry
  • Materials Science

Background:

  • Molecular imprinting is an emerging technique for creating synthetic polymers with specific recognition sites.
  • This method involves polymerizing functional monomers in the presence of a target molecule, known as the template.

Purpose of the Study:

  • To highlight the capabilities of molecular imprinting in creating selective polymers.
  • To discuss the potential commercial applications of these tailor-made materials.

Main Methods:

  • Polymerization of functional monomers.
  • Utilizing a template molecule during polymerization to create recognition sites.

Main Results:

  • The resulting polymers exhibit a high degree of stereo- and regiospecific selectivity.

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  • Demonstrated potential for tailor-made separation materials.

    • Conclusions:

    • Molecular imprinting offers a viable route to highly selective synthetic polymers.
    • These materials show realistic commercial potential in chiral separations and as antibody mimics.