[Osteosclerosis of the vertebrae in radiological diagnosis and its pathomechanism]

Primarily osteosclerosis is detected in secondary hyperparathyroidism, renal osteodystrophia and some renal tubular disorders. As mentioned, the sclerosis of vertebral body is often prominent in the regions adjacent to the endplates the typical "rugger-jersey-spine". In our study osteosclerosis was detected in about 10% of the patients with renal osteodystrophia. A still unknown defect in vitamin D-metabolism and a increased avidity of the skeleton for calcium may also involved. The result of this accumulation of steroid is a net increase of bone tissue, with or not mineralization. Conventional radiography is the method of choice in detecting typical features.