Case study of the anemic patient: epoetin alfa--focus on inflammation

Infection and inflammation are common problems in patients with end-stage renal disease. Both conditions can interfere with normal erythropoiesis and lead to a worsening of anemia and a suboptimal response to Epoetin alfa therapy. By understanding the pathophysiologic effects of infection and inflammation, assessing the patient's clinical status, and analyzing relevant laboratory values, nurses can intervene early and minimize the impact of these conditions on hematocrit.