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Abstract:
Recombinant human growth hormone was initially used as replacement therapy in children with short stature. As rhGH has become more readily available, it has been tested in a variety of other individuals who have delayed growth. Children with ESRD experience significant problems with delayed growth, thus replacement therapy with rhGH has been used in this population. resulting in improved growth velocity. The clinical significance of improved height may have a positive impact on the psychological well being of these children.