Related Experiment Videos
HLA antigens in Arab children with steroid-responsive nephrotic syndrome
M Zaki1, A S Daoud, Q A al Saleh
1Department of Paediatrics, Farwania Hospital, Kuwait.
Pediatric Nephrology (Berlin, Germany)
|February 1, 1994
Abstract:
Forty-eight Arab patients with steroid-responsive childhood nephrotic syndrome were studied for the frequency of HLA-A, -B, -C and -DR antigens. HLA-DR7 was significantly increased in the patient group (63% vs. 28%, P = 0.0002) confirming reports of a DR7 association in other ethnic groups and indicating a universal association with this antigen. HLA-CW6 was also significantly increased (44% vs. 21%, P corr. = 0.042). HLA-DQW1 was significantly reduced in the patients (29% vs. 57%, P corr. = 0.012) as was HLA-CW4 (6% vs. 24%, P corr. = 0.042).