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Subversion of host immune responses by viral superantigens
1Ludwig Institute for Cancer Research, Lausanne Branch, Epalinges, Switzerland.
Trends in Microbiology
|April 1, 1993
Abstract:
Recent experiments with mouse mammary tumor virus indicate that expression of a virally encoded superantigen by B cells and its subsequent recognition by T cells are essential steps for amplification of infection and virus transmission. Preliminary results suggest that superantigens may also be expressed during retroviral infection in humans.