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A new cytogenetic finding in an epithelioid sarcoma, t(8;22)(q22;q11)
J C Cordoba1, D M Parham, W H Meyer
1Department of Hematology/Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee.
Cancer Genetics and Cytogenetics
|February 1, 1994
Abstract:
We report a new translocation t(8;22)(q22;q11) in a single case of epithelioid sarcoma. The band involved in chromosome 22 is the same found in 70-80% of the case of Ewing's sarcoma/peripheral neuroepithelioma (PNET) with cytogenetic characterization. The histologic characteristics of this tumor were typical for epithelioid sarcoma. Immunohistochemical stains were also entirely consistent with this diagnosis, including non-reactivity with P30/32MIC2, a specific marker for Ewing's sarcoma/primitive neuroepithelioma.