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Updated: Aug 4, 2026

Electrochemiluminescence Assays for Human Islet Autoantibodies
Published on: March 23, 2018
Association between high concentration of antibodies to insulin and some diseases common in the elderly
M Wolk1, M Kieselstein, R Hamburger
1Geriatric Departments, Nofim Senior Housing, Herzog Hospital, Jerusalem, Israel.
Abstract:
Antibodies to insulin (IA) were measured by graded hemagglutination in 164 patients and in 90 control subjects aged 18-65 years. The greatest prevalence of these antibodies was found in patients with the organic mental syndrome, of whom 70% (n = 110) had an antibody concentration above the normal 95th percentile. Among patients with diabetes, hypertension and cerebrovascular accidents, 42% had a high concentration of IA, while in all other geriatric patients (n = 21) the concentration of these antibodies was within the normal range.
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