Related Experiment Videos
[Immunologic isolation of transplanted islets of Langerhans: microcapsules with defined molecular limits]
G Klöck1, U Siebers, A Pfeffermann
1Lehrstuhl für Biotechnologie, Biozentrum der Universität Würzburg.
Immunitat Und Infektion
|December 1, 1993
Abstract:
Immunoisolated transplantation of islets of Langerhans in barium alginate microcapsules is a promising therapeutic approach to cure diabetes. An improved membrane for the coating of barium alginate microcapsules has been developed. Chemically stable barium alginate microcapsules with a controlled molecular weight cutoff between 9400 and 40,500 D were obtained after coating of barium alginate capsules in Polybrene solutions. Microcapsules prepared by this new method were still freely permeable to low molecular weight substances.