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Related Concept Videos

Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...

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Related Experiment Video

Updated: Jul 22, 2026

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
10:35

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats

Published on: November 11, 2013

Risk factors for drug misuse in Pakistan

J S Gillis1, I A Tareen, H R Chaudhry

  • 1Oregon State University, Corvallis 97331.

The International Journal of the Addictions
|January 1, 1994
PubMed
Summary

Societal drug misuse risk factors identified in the United States were also found in Pakistan. This suggests that precursors for drug misuse are universal and not limited by cultural differences.

Area of Science:

  • Social Sciences
  • Psychiatry
  • Public Health

Background:

  • Drug misuse is a significant public health issue globally.
  • Previous research identified sociodemographic risk factors for drug misuse primarily in the United States.
  • Limited evidence exists on drug misuse risk factors in non-Western societies, particularly in Pakistan.

Purpose of the Study:

  • To identify sociodemographic risk factors for drug misuse in Pakistan.
  • To determine if previously identified risk factors in the United States are applicable in a Pakistani context.

Main Methods:

  • A case-control study was conducted in Pakistan.
  • Eleven sociodemographic variables, previously identified as predictors in the US, were assessed.
  • Groups of drug addicts (cases) and controls were compared based on these variables.

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A Procedure to Study Stress-Induced Relapse of Heroin Seeking after Punishment-Imposed Abstinence
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Last Updated: Jul 22, 2026

A Procedure to Study the Effect of Prolonged Food Restriction on Heroin Seeking in Abstinent Rats
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Published on: November 11, 2013

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
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Main Results:

  • Ten out of eleven sociodemographic variables successfully differentiated between drug addicts and controls in Pakistan.
  • Approximately 97% of the studied addicts were at risk for four or more factors.
  • 100% of controls were at risk for four or fewer factors, indicating a clear distinction.

Conclusions:

  • Sociodemographic risk factors for drug misuse appear to be universal and transcend cultural boundaries.
  • The findings support the applicability of US-based drug misuse risk factor models in Pakistan.
  • This research highlights the need for culturally sensitive yet universally applicable interventions for drug misuse prevention and treatment.