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Related Experiment Videos

Abdominal symptom associations in a longitudinal study

L Kay1, T Jørgensen

  • 1Medical Department C, Glostrup County Hospital, University of Copenhagen, Denmark.

International Journal of Epidemiology
|December 1, 1993
PubMed
Summary
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This study identified three common abdominal symptom clusters in a general population: digestive distress, acid reflux, and nausea. These symptom patterns remained consistent over a five-year follow-up period.

Area of Science:

  • Gastroenterology
  • Epidemiology
  • Public Health

Background:

  • Abdominal symptoms are common in the general population.
  • Understanding symptom associations can help define common gastrointestinal syndromes.

Purpose of the Study:

  • To assess associations between abdominal symptoms in a general population.
  • To confirm these associations in a five-year follow-up study.
  • To identify potential common abdominal syndromes.

Main Methods:

  • A sex- and age-stratified random sample from Copenhagen County, Denmark.
  • Questionnaire-based assessment of abdominal symptoms at baseline and 5-year follow-up.
  • Analysis of symptom associations by sex, age, and pain characteristics.

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Main Results:

  • Three consistent symptom clusters emerged: 1) borborygmi/altered stool/distension, 2) acid regurgitation/heartburn, and 3) nausea/vomiting.
  • Unspecified abdominal pain correlated with all clusters.
  • Pain related to stress, hunger, or defecation linked to the first cluster; epigastric pain and pain relieved by eating showed inconsistent associations.

Conclusions:

  • The identified symptom clusters represent distinct, common abdominal syndromes.
  • These syndromes exhibit stable associations over time within the general population.
  • Findings support the recognition of these clusters as clinically relevant gastrointestinal syndromes.