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[Intracranial meningiomas]
1Servicio de Neurocirugía, Complejo Hospitalario Metropolitano de la Caja de Seguro Social.
Abstract:
The author excised an intracranial meningioma from 28 patients, 17 women and 11 men, between 7 and 78 years of age, from 1974 to 1992. The tumor was located in the olfactory groove in 4 patients, in the cerebral convexity in another 4, in the falx in 8 (3 in the frontal and 5 in the parietal region). In 6 patients, the meningioma was found in the inner one third and in 1 in the middle third of sphenoid; in 1, in the clivus, in 1 in the petrous bone; in 2 patients the tumor was located in the tubercle of the sella turcica and in another patient it was in the cerebello-pontine angle. Total resection of the meningioma was accomplished in 16 patients (57.1%) because the tumor was in an accessible area. The tumor recurred in one patient, who died 5 years post operatively. In 8 (28.5%) of 12 patients in whom subtotal resection was done, post operative radiation was used, and in 3 of them recurrence occurred in less than 5 years after completion of treatment and in one, in less than 10. In 3 of the remain 4 patients, in whom subtotal resection was done but were not followed by radiation therapy, recurrence also occurred before 5 years post surgery, and in 1 patient at the end of 5 years.
Insights
Surgical resection of intracranial meningiomas offers a good prognosis, with total resection achieving better long-term outcomes. Subtotal resection may require adjuvant radiation therapy to prevent tumor recurrence.
Area of Science:
- Neurosurgery
- Oncology
Context:
- Intracranial meningiomas represent a significant subset of primary brain tumors.
- Surgical management is the primary treatment modality for these tumors.
Purpose:
- To evaluate the outcomes of surgical resection for intracranial meningiomas.
- To assess the impact of total versus subtotal resection and adjuvant radiation therapy on recurrence rates.
Summary:
- This study reviewed 28 patients who underwent surgical excision of intracranial meningiomas between 1974 and 1992.
- Total resection was achieved in 57.1% of cases, with one recurrence. Subtotal resection in 12 patients led to recurrence in 3/8 treated with radiation and 3/4 not treated with radiation within 5 years.
Impact:
- Total resection is associated with a lower risk of recurrence for accessible intracranial meningiomas.
- Adjuvant radiation therapy following subtotal resection may reduce, but not eliminate, the risk of recurrence.