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[Breast lymphoma]

P Panzarola1, P Bosso, A Stocchi

  • 1Istituto di Radiologia, Università degli Studi, Perugia.

La Radiologia Medica
|March 1, 1994
PubMed
Summary

Primary and secondary breast lymphomas are rare, with secondary lymphomas being the most common metastatic breast cancer. Imaging findings vary, sometimes mimicking benign conditions, underscoring the need for biopsy for accurate diagnosis.

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Area of Science:

  • Oncology
  • Radiology
  • Pathology

Context:

  • Primary malignant lymphomas of the breast are rare, accounting for 0.12%-0.53% of all breast cancers.
  • Secondary lymphomas are uncommon but represent the most frequent metastatic breast cancers.
  • This study reviewed 6 cases (1 primary, 5 secondary) observed between 1989-1992.

Purpose:

  • To report the clinical, mammographic, and ultrasound (US) features of breast lymphoma.
  • To highlight the diagnostic challenges and review relevant literature on this unusual condition.

Summary:

  • Observed 6 cases of breast lymphoma in women aged 52-67 years.
  • Primary lymphoma was unilateral; secondary lymphomas were diffuse/bilateral (4 cases) or unilateral/nodular (1 case).
  • Clinical and imaging findings were often suggestive of malignancy, though mammography sometimes showed benign patterns, necessitating biopsy for definitive diagnosis of non-Hodgkin's lymphoma.

Impact:

  • Emphasizes the importance of considering breast lymphoma in differential diagnoses for breast masses.
  • Highlights the variability in imaging presentation, which can sometimes obscure diagnosis.
  • Underscores the critical role of biopsy in confirming breast lymphoma, particularly non-Hodgkin's types.

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