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Electron-beam therapy in scleredema adultorum with associated monoclonal hypergammaglobulinaemia
C Angeli-Besson1, M C Koeppel, P Jacquet
1Department of Dermatology, CHU la Timone, Marseille, France.
The British Journal of Dermatology
|March 1, 1994
Abstract:
We report a case of scleredema adultorum (Buschke's disease) associated with an IgA kappa monoclonal hypergammaglobulinaemia. A significant improvement in the skin was obtained with electron-beam therapy. Scleredema would appear to be linked to monoclonal hypergammaglobulinaemia, but the relationship between the skin disorder and the immunoglobulin abnormality remains to be elucidated.