[Acquired hemophilia and rheumatoid arthritis. Value of intravenous immunoglobulins]
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L Struillou1, M Fiks-Sigaud, J H Barrier
1Service de Médecine Interne, Hôtel-Dieu, Nantes.
Abstract:
The authors report an exceedingly rare complication of rheumatoid arthritis, i.e. acquired hemophilia due to anti-factor VIII autoantibody production. Treatment with intravenous immune globulin ensured control of hemorrhagic manifestations by inducing a transient rise in factor VIII level.