Related Experiment Video
Updated: Aug 10, 2026
13:08
Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
Absent factor II in systemic lupus erythematosus. Immunologic studies and response to corticosteroid therapy
Arthritis and Rheumatism
|January 1, 1976
Abstract:
This report describes a patient with active systemic lupus erythematosus (SLE) who evidenced severe bleeding consequent to a profound and isolated reduction in plasma factor II (prothrombin) activity. Absence of the factor is documented by immunologic means and its return after corticosteroid therapy is demonstrated. The authors recommend inclusion of this acquired coagulopathy among other more traditional diagnostic manifestations of SLE.
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