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Related Concept Videos

Burn Injuries01:22

Burn Injuries

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Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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What are Cells?01:07

What are Cells?

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Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
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Tissues01:18

Tissues

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Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
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What is Cell Signaling?02:03

What is Cell Signaling?

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Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
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Chemistry of the Cell02:58

Chemistry of the Cell

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The cell is chemically composed of water, organic molecules and inorganic ions.
Water
The polarity of the water molecule and its resulting hydrogen bonding makes water a unique substance with special properties that are intimately tied to the processes of life. Life originally evolved in an aqueous environment, and most of an organism’s cellular chemistry and metabolism occur inside the aqueous contents of the cell’s cytoplasm. Special properties of water are its high heat capacity...
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Concentration Cells02:41

Concentration Cells

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A concentration cell is a type of a  voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
Consider the following voltaic cell:
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Related Experiment Video

Updated: Feb 11, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
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Development of Compendium for Esophageal Squamous Cell Carcinoma

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[Squamous cell carcinoma arising from burn scars]

Z X Zhang1

  • 1Department of Pathology, Yichang Medical College.

Zhonghua Zheng Xing Shao Shang Wai Ke Za Zhi = Zhonghua Zheng Xing Shao Shang Waikf [I.E. Waike] Zazhi = Chinese Journal of Plastic Surgery and Burns
|November 1, 1993
PubMed
Summary

Squamous cell carcinoma (SCC) in burn scars is rare, representing 9.6% of skin SCC cases. These malignancies typically develop decades after the initial burn injury.

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Context:

  • Burn scars are a known risk factor for developing skin malignancies.
  • Squamous cell carcinoma (SCC) is the most common skin cancer to arise in burn scars.

Purpose:

  • To review and analyze clinicopathological features of SCC in burn scars.
  • To understand the growth patterns and diagnostic challenges of burn scar carcinoma.

Summary:

  • A review of 37 cases of squamous cell carcinoma (SCC) arising in burn scars diagnosed between 1963-1991.
  • SCC in burn scars accounted for 9.6% of all skin SCC cases during the study period.
  • Mean age of patients was 43 years, with a mean interval of 35.7 years from burn to SCC diagnosis.
  • Macroscopic findings included infiltrative ulcerative and exophytic cauliflower-like carcinomas.

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  • Microscopically, most SCCs were well-differentiated (26 cases).

    • Impact:

    • Highlights the long-term risk of malignancy in burn scars.
    • Provides insights into the clinical and pathological characteristics of this rare condition.
    • Aids in early diagnosis and management of burn scar SCC.