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[The preparation of 99mTc-NGA instant lyophilized kit for hepatic imaging]
Abstract:
The preparation of one-step kit for the 99mTc labelled galactosyl-neo-glycoalbumin (NGA) using SnCl2 reduced method was reported in this paper. We developed a method of quality control and established the optimum scheme of technetium labelling on the basis of exploring the effects of varied labelled conditions on radiochemical purity. Our data indicates : (a) the kit is sterile, pyrogen-free and no toxic effects; (b) the operation is simple and fast; (c) its period of validity lasts no less than 3 months; (d) the radiochemical purity > 95%; (e) the stability of 99mTc-NGA in vitro > 4 hours; (f) the results of animal imaging and clinical probation are satisfactory.