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Related Experiment Videos

[Wissler's allergic subsepsis]

R Fink-Puches1, J Smolle, H Kerl

  • 1Universitätsklinik für Dermatologie und Venerologie, Graz.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|February 1, 1994
PubMed
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Wissler

Area of Science:

  • Rheumatology and Immunology
  • Pediatric Rheumatology

Background:

  • Wissler's subsepsis allergica (Wissler-Fanconi syndrome) is a rare condition.
  • It presents with fever, rash, elevated white blood cell count, and joint pain.

Observation:

  • A 20-year-old female patient exhibited typical signs of Wissler's subsepsis allergica.
  • Early differentiation from septicemia can be challenging.

Findings:

  • The case highlights the characteristic symptoms: polymorphous exanthemas, recurrent high fever, leukocytosis, and arthralgia.
  • This syndrome's classification remains debated, with some linking it to Still's disease and others to a distinct entity.

Implications:

  • Wissler's subsepsis allergica should be considered in patients with transient polymorphous exanthema, fever, leukocytosis, and arthralgia.

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  • Accurate diagnosis is crucial for appropriate management and prognosis, especially given its potential overlap with juvenile rheumatoid arthritis.