Quadruplet pregnancy in a 51-year-old menopausal woman following oocyte donation

A quadruplet pregnancy occurred in a woman 51 years of age following oocyte donation and embryo transfer. Successful pregnancy occurred following two previously unsuccessful attempts. The patient underwent a selective reduction of her pregnancy to two fetuses at approximately 13 weeks gestational age. Her pregnancy continued uneventfully and she underwent the delivery of two viable infants at 38 weeks gestational age by Caesarean section. This case represents the first quadruplet pregnancy to be established in a woman of 50 years of age or older. It illustrates both the benefits and risks of oocyte donation to women of advanced reproductive age.