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[Yellow nail syndrome]

M Hausmann1, R Keller

  • 1Pneumologische Abteilung, Klinik Barmelweid.

Pneumologie (Stuttgart, Germany)
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

Yellow Nail Syndrome, a rare condition causing nail dystrophy, lymphedema, and pleural effusion, is detailed in a case study. Oral zinc shows promise for treating nail and lymphedema symptoms.

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Area of Science:

  • Medicine
  • Genetics
  • Dermatology

Background:

  • Yellow Nail Syndrome (YNS) is a rare disorder characterized by distinct clinical manifestations.
  • It involves yellowish, dystrophic nails, lymphedema, and recurrent pleural effusions.

Observation:

  • A case of a 53-year-old woman with YNS is presented, highlighting its rare occurrence.
  • A literature review was conducted to identify associated clinical features of YNS.

Findings:

  • The pathogenesis of YNS involves lymphatic drainage system dysfunction, inherited in an autosomal-dominant pattern.
  • While no definitive cure exists, topical tocopherol may improve nail appearance.
  • Recent findings suggest oral zinc application may benefit both nail dystrophy and lymphedema in YNS patients.

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Implications:

  • This case and review contribute to understanding the diverse clinical spectrum of YNS.
  • Further research into the pathogenesis of lymphatic dysfunction in YNS is warranted.
  • Oral zinc presents a potential therapeutic avenue for managing YNS symptoms, warranting further clinical investigation.