Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies01:27

Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies

Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Pulmonary Function Tests01:25

Pulmonary Function Tests

Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Chronic Obstructive Pulmonary Disease II: Emphysema01:23

Chronic Obstructive Pulmonary Disease II: Emphysema

Emphysema, a major phenotype of chronic obstructive pulmonary disease (COPD), is characterized by irreversible destruction of alveolar walls and permanent enlargement of distal airspaces. Unlike chronic bronchitis, which primarily affects the airways, emphysema predominantly involves the lung parenchyma, where structural damage leads to airflow limitation.PathophysiologyIt most commonly results from prolonged exposure to cigarette smoke and other toxic gases, particularly cigarette smoke.
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

RETROGRADE INTRARENAL LITHOTRIPSY USING DISPOSABLE FLEXIBLE URETEROSCOPE.

Georgian medical news·2024
Same author

CHANGES IN MALE REPRODUCTIVE HORMONES IN PATIENTS WITH COVID-19.

Georgian medical news·2023
Same author

Ventricular longitudinal shortening is an independent predictor of death in heart failure patients with reduced ejection fraction.

Scientific reports·2021
Same author

Prevalence and subtype distribution of Blastocystis sp. in cattle from Pahang, Malaysia.

Tropical biomedicine·2021
Same author

The Lebanese left ventricular assist device experience, a success story despite the odds.

Journal of cardiothoracic surgery·2020
Same author

New embedding and staining systems PrestoCHILL and Presto stainer for application in the advancement of Mohs micrographic surgery.

British journal of biomedical science·2017

Related Experiment Video

Updated: May 22, 2026

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
08:58

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

Published on: July 10, 2018

Pulmonary function in symptom-free asthmatics

I Yaacob1, M Mohammad

  • 1Department of Medicine, School of Medical Sciences, Hospital Universiti Sains Malaysia, Kelantan.

Singapore Medical Journal
|December 1, 1993
PubMed
Summary

Asthma can lead to lasting airflow obstruction, even when symptoms are absent. Spirometry tests reveal reduced lung function in most clinically remitted asthma patients, highlighting a disconnect between symptoms and actual respiratory health.

Area of Science:

  • Pulmonology
  • Respiratory Medicine
  • Clinical Investigation

Background:

  • Asthma is a chronic respiratory disease characterized by airway inflammation.
  • Clinical remission in asthma is often defined by the absence of symptoms.
  • The long-term impact of asthma on lung function, even in remission, requires further investigation.

Purpose of the Study:

  • To assess the respiratory function of adult asthmatic patients in clinical remission.
  • To determine the prevalence of normal spirometry results in asthma patients experiencing remission.
  • To investigate the relationship between asthma symptoms and objective respiratory function tests.

Main Methods:

  • Spirometry was performed on 75 adult patients with asthma in clinical remission.

More Related Videos

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
08:44

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method

Published on: February 2, 2024

Related Experiment Videos

Last Updated: May 22, 2026

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
08:58

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

Published on: July 10, 2018

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
06:11

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults

Published on: February 9, 2022

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
08:44

Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method

Published on: February 2, 2024

  • Key spirometry parameters including vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in one second (FEV1), maximum mid-expiratory flow rate (MMF), and peak expiratory flow rate (PEFR) were measured.
  • Results were analyzed to identify deviations from normal lung function values.

    • Main Results:

    • Only 8.3% of the asthmatic patients in clinical remission exhibited normal spirometry results.
    • The majority of subjects demonstrated reduced lung function across multiple spirometry measures (VC, FVC, FEV1, MMF, PEFR).
    • A significant portion of patients showed evidence of airflow obstruction despite clinical remission.

    Conclusions:

    • Asthma can result in irreversible airflow obstruction, persisting even when symptoms are not apparent.
    • There is a poor correlation between the subjective experience of asthma symptoms and objective respiratory function test outcomes.
    • Regular spirometry monitoring is crucial for asthmatic patients to detect persistent lung function deficits.