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[Peripheral arterial occlusive disease--acute intervention and after-care]
1Medizinische Klinik und Poliklinik, Innere Medizin A, Westfälische Wilhelms-Universität, Münster.
Zeitschrift Fur Kardiologie
|January 1, 1993
Summary
Peripheral arterial occlusive disease requires swift treatment for acute ischemia. Management strategies include surgery, thrombolysis, and angioplasty, with antiplatelet drugs crucial for long-term care.
Area of Science:
- Vascular Surgery
- Interventional Radiology
- Cardiology
Context:
- Acute limb ischemia from atherosclerosis necessitates urgent intervention.
- Multidisciplinary collaboration among vascular surgeons, angiologists, and radiologists is vital.
- Thrombotic or thromboembolic events are primary causes of peripheral arterial occlusive disease.
Purpose:
- To outline therapeutic strategies for acute peripheral arterial ischemia.
- To discuss the roles of surgical management, local thrombolysis, and percutaneous revascularization.
- To review the use of anticoagulation and antiplatelet therapies.
Summary:
- Surgical management is preferred for complete ischemia and suprainguinal occlusions.
- Incomplete ischemia and infrainguinal occlusions may benefit from thrombolysis and angioplasty.
- No significant efficacy or safety differences exist among major thrombolytic agents.
- Heparinization and antiplatelet drugs are essential peri- and post-procedural treatments.
- Long-term antiplatelet therapy is recommended for all patients.
Impact:
- Informs clinical decision-making for acute limb ischemia.
- Highlights the importance of a coordinated, evidence-based approach.
- Emphasizes the role of pharmacotherapy in managing peripheral arterial occlusive disease.