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Group B streptococcal metastatic endophthalmitis
H P Nagelberg1, D E Petashnick, K W To
1Department of Ophthalmology, Rhode Island Hospital, Brown University School of Medicine, Providence 02903.
Abstract:
Reports of invasive Group B Streptococcus infection in adults with underlying medical conditions have been increasing. Ocular infection with this organism is unusual. Metastatic endophthalmitis in adults caused by this organism has been reported rarely and has only been associated with endocarditis. We encountered two cases of Group B streptococcal metastatic endophthalmitis in adults who did not have endocarditis. These cases reflect the increasing incidence of invasive Group B Streptococcus infection with its varying manifestations. Additionally, they emphasize the importance of considering this pathogen as a cause of metastatic endophthalmitis in adults with predisposing illnesses.
Insights
Invasive Group B Streptococcus infections are rising in adults. This study highlights rare cases of metastatic endophthalmitis caused by this bacteria, even without endocarditis, emphasizing its varied manifestations.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Invasive Group B Streptococcus (GBS) infections are increasingly reported in adults, particularly those with underlying health conditions.
- Ocular GBS infections are uncommon, with metastatic endophthalmitis rarely documented and typically linked to endocarditis.
Observation:
- Two adult patients presented with metastatic endophthalmitis due to Group B Streptococcus.
- Neither patient had a diagnosis of endocarditis, a previously established association.
Findings:
- This presentation demonstrates that Group B Streptococcus can cause metastatic endophthalmitis in adults without endocarditis.
- The cases underscore the evolving and diverse clinical presentations of invasive GBS infections.
Implications:
- Clinicians should consider Group B Streptococcus as a potential cause of metastatic endophthalmitis in adults, especially those with predisposing medical conditions.
- Increased awareness of GBS's varied manifestations is crucial for timely diagnosis and management of invasive infections.