Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Improving empiric antibiotic selection using computer decision support

R S Evans1, D C Classen, S L Pestotnik

  • 1Department of Clinical Epidemiology, LDS Hospital, Salt Lake City, UT 84143.

Archives of Internal Medicine
|April 25, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of anastomotic leak following restorative rectal cancer resection-a multi-centre retrospective audit in Ireland.

Irish journal of medical science·2026
Same author

Digital endoscopic characterisation of significant rectal neoplasia: A video vignette.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2025
Same author

Local excision of rectal neoplasia: a real-world survey of current practices and perspectives.

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy·2025
Same author

Preoperative anorectal manometry as a predictor of function after ileal pouch anal anastomosis: a systematic review and meta-analysis.

Techniques in coloproctology·2024
Same author

Prolonged interval to surgery following neoadjuvant chemoradiotherapy in locally advanced rectal cancer: A meta-analysis of randomized controlled trials.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·2024
Same author

Centralisation of rectal cancer care has improved patient survival in the republic of Ireland.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2021
Same journal

Elevated CK-MB With Normal Total Creatine Kinase Levels in Patients Undergoing Maintenance Hemodialysis-Reply.

Archives of internal medicine·2017
Same journal

Occult Carbon Monoxide Poisoning-Reply.

Archives of internal medicine·2017
Same journal

Acquired Immune Deficiency Syndrome-Reply.

Archives of internal medicine·2017
Same journal

Heparin Side Effects-Reply.

Archives of internal medicine·2017
Same journal

Humanizing primary care medicine begins with stress.

Archives of internal medicine·2017
Same journal

Legend omitted and number misrepresented.

Archives of internal medicine·2013
See all related articles

A computerized antibiotic consultant improved empiric antibiotic selection for infections. The system achieved higher susceptibility rates and faster appropriate antibiotic ordering compared to physician judgment alone.

Area of Science:

  • Medical Informatics
  • Infectious Diseases
  • Clinical Decision Support

Background:

  • Empiric antibiotic therapy is often initiated before culture and susceptibility results are available.
  • Physicians require tools to optimize empiric antibiotic selection.
  • Computerized decision support systems can aid in this process.

Purpose of the Study:

  • To develop and evaluate a computerized antibiotic consultant.
  • To assess the impact of the consultant on empiric antibiotic selection.
  • To compare consultant recommendations with physician choices.

Main Methods:

  • A two-stage randomized study design was employed.
  • Compared consultant-suggested antibiotics with 482 culture and susceptibility results.

Related Experiment Videos

  • Evaluated physician antibiotic orders before and after consultant use.

    • Main Results:

    • The antibiotic consultant achieved 94% pathogen susceptibility, compared to 77% for physician orders (P < .001).
    • Appropriate antibiotics were ordered significantly faster with the consultant (within 12 hours vs. 21 hours mean time).
    • Physicians reported high satisfaction and perceived improvement in patient care.

    Conclusions:

    • Computer-based medical record information can enhance empiric antibiotic selection.
    • Decision support tools are valuable for optimizing antibiotic therapy.
    • The study demonstrates the efficacy of a computerized antibiotic consultant.