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Effect of sulfated polysaccharides on hepatocyte adhesion
M Kunoú1, T Akaike, K Hatanaka
1Department of Biomolecular Engineering, Tokyo Institute of Technology, Yokohama, Japan.
Journal of Biomaterials Science. Polymer Edition
|January 1, 1993
Abstract:
The effects of sulfated polysaccharides on hepatocyte adhesion on the polystyrene dish and fibronectin-coated dish were investigated. Dextran sulfate and synthetic mannopyranan sulfate slightly inhibited hepatocyte adhesion on fibronectin-coated dish, while heparin showed no effect. On the other hand, hepatocyte adhesion on polystyrene dishes was stimulated in the presence of sulfated polysaccharides in the medium.