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Updated: Aug 7, 2026

Using Caco-2 Cells to Study Lipid Transport by the Intestine
Published on: August 20, 2015
[The possibility of using carbon enterosorbents for normalizing cholesterol metabolism]
Abstract:
The kinetics of bile acids (BA) and cholesterol adsorption from biological fluids (bile) and reference solutions on carbon SCN were compared with conventional medical carbon with the view of elucidating the role of adsorption in improving cholesterol metabolism. It was found that the adsorptive capacity of carbon adsorbents is determined, primarily, by their porous structure as well by the chemical properties of the adsorbing surface. The enterosorbents were tested both in experimental animals and in clinical trials and are now successfully employed for preventing and treating atherosclerosis as well as for normalizing lipid metabolism. A procedure for surgical treatment combined with adsorptive detoxication (enterosorption) for patients with obstructive jaundice has been developed.
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