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Wound seeding associated with endometrial cancer
M G Curtis1, M P Hopkins, B Cross
1Department of Obstetrics & Gynecology, Northeastern Ohio Universities College of Medicine, Akron General Medical Center 44307.
Gynecologic Oncology
|March 1, 1994
Summary
Recurrent endometrial cancer can manifest as an abdominal wall mass due to surgical wound seeding. Early detection and radical resection of isolated metastases offer potential benefits for patients with endometrial cancer.
Area of Science:
- Gynecologic Oncology
- Surgical Oncology
Background:
- Endometrial cancer, a common gynecologic malignancy, typically requires surgical management.
- Positive peritoneal cytology after surgery indicates a higher risk of recurrence.
Observation:
- A patient with well-differentiated endometrial adenocarcinoma developed an isolated anterior abdominal wall mass two years post-surgery.
- The recurrence was likely due to wound seeding during the initial surgical procedure.
Findings:
- The patient underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy, followed by 32P therapy for positive peritoneal washings.
- A large lower incision mass was surgically resected using a myocutaneous flap, with no evidence of intra-abdominal disease.
Implications:
- Radical resection of isolated metastases may improve outcomes in endometrial cancer patients.
- Close monitoring for incisional recurrences is crucial for patients with positive cytology after endometrial cancer surgery.