Recurrent asystole associated with vasovagal reaction during venipuncture

A patient with a documented history of 2 asystolic episodes associated with venipuncture demonstrates the profound cardioinhibitory effects that vasovagal reactions to blood and injury ("blood-injury phobia") can produce. In approaching a patient with blood-injury phobia, the clinician should place the patient in the Trendelenburg position, apply a cardiac monitor, administer oxygen, and consider the need for atropine, transcutaneous pacing, and cough cardiopulmonary resuscitation (CPR) prior to venipuncture. Diagnosis of vasovagal syncope is discussed. Long-term prophylactic interventions may be beneficial for certain patients.