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Antimicrobial activity of natural and semisynthetic diterpenoids from Sideritis spp
M E Rodríguez-Linde1, R M Díaz, A García-Granados
1Department of Microbiology, University of Granada, Spain.
Microbios
|January 1, 1994
Abstract:
The antimicrobial activity of 22 natural diterpenoids of endemic Sideritis from Eastern Andalusia (Spain) is described. Only ent-kaur-16-ene foliol and ent-beyer-15-ene isopusillatriol proved to be active towards Gram-positive and acid-fast bacteria. The introduction of a ketonic group at C-15 on ent-kaur-16-enic systems produced a remarkable degree of activity.