Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Evaluation of deviating liver tests in ambulatory practice]

J J Gonvers1

  • 1Division de gastro-entérologie, P.M.U., Lausanne.

Schweizerische Medizinische Wochenschrift
|March 26, 1994
PubMed
Summary

Disturbed hepatic function tests are common. Understanding liver function tests and classifying hepatobiliary diseases by hepatocellular necrosis or cholestasis aids diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Hepatology].

Revue medicale suisse·2006
Same author

[When and how to treat hepatitis B and C?].

Revue medicale suisse·2005
Same author

[Auto-immune liver diseases and their treatment].

Revue medicale suisse·2005
Same author

[Complications of liver cirrhosis: oesophageal varices, ascites and hepato-cellular carcinoma].

Revue medicale suisse·2005
Same author

Do explicit appropriateness criteria enhance the diagnostic yield of colonoscopy?

Endoscopy·2002
Same author

Helicobacter pylori eradication treatment does not benefit patients with nonulcer dyspepsia.

The American journal of gastroenterology·2001

Area of Science:

  • Hepatology
  • Clinical Biochemistry
  • Diagnostic Medicine

Context:

  • Elevated liver function tests (LFTs) are frequently encountered in clinical practice.
  • Physician approach relies on understanding LFTs and hepatobiliary disease indicators, not rigid algorithms.
  • Distinguishing between hepatocellular injury and cholestasis is crucial for diagnosis.

Purpose:

  • To outline the diagnostic approach to abnormal liver function tests.
  • To categorize hepatobiliary diseases based on LFT patterns.
  • To highlight common causes of isolated transaminase elevation.

Summary:

  • Liver function tests are broadly classified into non-specific and specific types.
  • Hepatocellular necrosis is indicated by elevated transaminases, while cholestasis involves alkaline phosphatases and gamma-glutamyl transferase.
  • Chronic hepatitis C, alcoholism, and obesity are frequent causes of isolated transaminase elevation.

Impact:

  • Facilitates etiological diagnosis of liver diseases.
  • Provides a framework for interpreting abnormal LFTs.
  • Aids clinicians in managing patients with hepatic dysfunction.

Related Experiment Videos