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[The effect of remote-controlled shock-wave lithotripsy on kidney function]
Urologiia I Nefrologiia
|November 1, 1993
Summary
Remote impulse lithotripsy (RIL) temporarily impacts kidney function, indicated by reduced leucine arylamidase (LAA) excretion. Recovery time for LAA activity depends on stone complexity and RIL session number.
Area of Science:
- Nephrology
- Urology
- Biochemistry
Background:
- Nephroureterolithiasis, or kidney and ureter stones, affects renal function.
- Remote Impulse Lithotripsy (RIL) is a common treatment for kidney stones.
- Leucine arylamidase (LAA) is a biomarker for renal function.
Observation:
- Leucine arylamidase (LAA) excretion in urine was measured in 79 patients with nephroureterolithiasis before and after RIL.
- Patients were categorized into uncomplicated (Group 1) and complicated (Group 2) groups, with some receiving a second RIL session.
- Stone location and inflammation presence were noted.
Findings:
- RIL significantly reduced LAA excretion in Group 1 patients.
- LAA activity recovery took 6-7 days in Group 1 and 10-14 days in Group 2.
- Repeated RIL sessions, especially in Group 2, led to faster LAA activity enhancement.
- Calyceal and intrarenal pelvic stones showed higher LAA elevation than ureteral stones.
Implications:
- RIL has a short-term impact on renal function.
- The effect of RIL on kidney function is influenced by inflammation, number of sessions, stone location, and impulse count.
- Monitoring LAA excretion can help assess renal recovery post-RIL.