[The kinetics of oxygen transport by the blood]

A method for calculation of oxygen metabolism kinetics in vivo for different blood pH and for different inhaled air pressure is proposed. It is based on joint solution of equations of oxygen balance in lungs and in capillaries of oxygen-consuming tissues. All calculations were carried out within the physiological range of the above parameters. The value of maximum physical load was estimated for each set of the parameters. This load was evaluated in respect to the maximal oxygen consumption possible under conditions selected. Only data borrowed from normal physiology were used in calculations. It was shown that oxyhemoglobin dissociation curve shifts (for example, caused by blood pH deviation from its norm) does not have substantial influence on the organism ability to produce work, on its supplement with the oxygen, and can not cause pathologies at acidosis and alkalosis. This new result was obtained due to adoption of strict equality of the oxygen flows absorbed by blood in the lungs and of the oxygen given back by the blood in capillaries of the oxygen-consuming tissues.