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Factors associated with abruptio placentae in preterm deliveries
A Spinillo1, E Capuzzo, L Colonna
1Department of Obstetrics and Gynecology, University of Pavia, IRCCS Policlinico S. Matteo, P. Ie Golgi, Italy.
Objective:
To evaluate risk factors associated with occurrence of abruptio placentae in preterm deliveries.
Methods:
Risk factors were evaluated in 55 consecutive index cases of abruptio placentae and 726 control patients delivered between 24-36 weeks' gestation.
Results:
In logistic regression analysis abruptio placentae was associated with a low number of antenatal visits, smoking in pregnancy, hypertension, intravenous drug abuse and a history of recent abdominal trauma. Among hypertensive disorders of pregnancy, preeclampsia superimposed on chronic hypertension was associated with the highest risk of premature placental separation. Finally, there was a significant trend relating duration of premature rupture of membranes with abruptio placentae (chi-square for trend = 3.93, p = 0.047).
Conclusions:
Several risk factors seem strongly associated with abruptio placentae in preterm deliveries; the presence of these risk factors should dictate intensive surveillance.