Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human immunodeficiency virus-associated nephropathy: current concepts

H D Stone1, R G Appel

  • 1Department of Medicine, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157.

The American Journal of the Medical Sciences
|March 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of virus strain and antigen mass on efficacy of H5 avian influenza inactivated vaccines.

Avian pathology : journal of the W.V.P.A·2016
Same author

Detection of Salmonella enteritidis in incubated pools of egg contents by fluorescence polarization and lateral flow immunodiffusion.

Poultry science·2003
Same author

Detection of Salmonella enteritidis-specific immunoglobulin A antibodies in crop samples from chickens infected with Salmonella enteritidis.

Poultry science·2003
Same author

Detection of experimental Salmonella enteritidis and S. typhimurium infections in laying hens by fluorescence polarization assay for egg yolk antibodies.

Poultry science·2002
Same author

Intermittent severe abdominal pain with normal peritoneal fluid findings on presentation.

Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis·2001
Same author

Application of the agar gel precipitin test to detect antibodies to Salmonella enterica serovar enteritidis in serum and egg yolks from infected hens.

Poultry science·2000

HIV-associated nephropathy is a distinct kidney disease in HIV patients, characterized by rapid progression to kidney failure. Differentiating it from other kidney diseases is crucial for patient outcomes.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Virology

Background:

  • HIV infection is increasingly linked to a specific form of kidney disease.
  • This condition contributes significantly to morbidity and mortality in affected individuals.
  • Risk factors include Black race and intravenous drug use.

Purpose of the Study:

  • To describe the characteristics of HIV-associated nephropathy (HIVAN).
  • To differentiate HIVAN from other renal pathologies, such as heroin-associated nephropathy.
  • To discuss the unclear pathogenesis and potential therapeutic interventions for HIVAN.

Main Methods:

  • Histopathological examination using light and electron microscopy.
  • Clinical assessment of proteinuria and progression to end-stage renal disease.

Related Experiment Videos

  • Review of existing literature on HIVAN and its associated factors.

    • Main Results:

    • HIVAN presents with nephrotic-range proteinuria and rapid progression to end-stage renal disease.
    • Microscopic findings include diffuse sclerosing glomerulopathy and tubulointerstitial disease.
    • Tubuloreticular inclusions are characteristic on electron microscopy.
    • HIVAN can be distinguished from heroin-associated nephropathy.

    Conclusions:

    • Accurate diagnosis of HIVAN is critical due to prognostic and therapeutic implications.
    • The pathogenesis of HIVAN remains multifactorial and requires further investigation.
    • Potential benefits of zidovudine therapy warrant further study.
    • Patient survival is closely tied to HIV disease stage, with limited benefit from dialysis in advanced AIDS.