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Related Experiment Videos

Sickle cell trait and stroke in children

M D Partington1, K E Aronyk, S E Byrd

  • 1Division of Neurosurgery, Children's Memorial Hospital, Chicago, Ill. 60614.

Pediatric Neurosurgery
|January 1, 1994
PubMed
Summary

Stroke is rare in sickle cell trait, but a 12-year-old experienced a posterior circulation infarct. A normal variant vertebral artery may have contributed to this rare pediatric stroke event.

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Area of Science:

  • Neurology
  • Hematology
  • Pediatrics

Background:

  • Cerebrovascular complications are common in sickle cell anemia, frequently causing stroke in children.
  • Stroke associated with sickle cell trait is rare, with limited documented cases in pediatric patients.

Observation:

  • A 12-year-old male with sickle cell trait presented with a posterior circulation infarct.
  • The patient also exhibited a normal variant of the vertebral artery, a potential contributing factor.

Findings:

  • This case highlights a rare instance of stroke in a pediatric patient with sickle cell trait.
  • The presence of a normal variant vertebral artery is discussed as a possible risk factor.

Implications:

  • Further research is needed to understand the specific risk factors for stroke in individuals with sickle cell trait.
  • This case underscores the importance of considering cerebrovascular events even in seemingly low-risk conditions like sickle cell trait.

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