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Psychogenic seizures in adults: a longitudinal analysis
M E Lancman1, T A Brotherton, J J Asconapé
1Department of Neurology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC.
Seizure
|December 1, 1993
Summary
This study analyzed 93 adults with psychogenic seizures (PS), finding hysteroid traits, coping issues, and depression common. While 25.4% of patients achieved seizure freedom, no clear predictors of poor prognosis were identified.
Area of Science:
- Neurology
- Psychiatry
- Clinical Psychology
Background:
- Psychogenic seizures (PS) are a complex neurological and psychiatric condition.
- Understanding the clinical characteristics and psychosocial factors is crucial for effective management.
Purpose of the Study:
- To analyze the clinical characteristics, psychosocial background, neuropsychological findings, and outcomes of adults with psychogenic seizures.
- To identify potential predictors of prognosis in this patient population.
Main Methods:
- Retrospective analysis of 93 adult patients diagnosed with psychogenic seizures.
- Evaluation included clinical assessment, psychosocial history, and neuropsychological testing.
- Follow-up data was collected to assess seizure status and social impact.
Main Results:
- The study included 93 adults (86% female, mean age 31.7 years) with psychogenic seizures.
- Neuropsychological testing revealed prevalent hysteroid traits, maladaptive coping mechanisms, and depression.
- A history of sexual abuse was reported in 10.7% of cases.
- Significant social impact was observed, with 34 of 62 working patients unable to work post-diagnosis.
- After a mean follow-up of 60.7 months in 63 patients, 16 (25.4%) became seizure-free.
- No significant predictors of poor prognosis were identified.
Conclusions:
- Psychogenic seizures in adults are associated with significant psychosocial challenges, including underlying psychiatric conditions and substantial social disability.
- While a quarter of patients achieved seizure freedom, the prognosis remains variable without clear predictive factors.
- Further research into integrated treatment approaches addressing both neurological and psychological aspects is warranted.
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