Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cluster headache: pulse rate changes evoked by hyperoxia and hypoxia

J M Shen1, J Schaanning

  • 1Department of Neurology, Rui Jin Hospital, Shanghai Second Medical University, China.

Headache
|February 1, 1994
PubMed
Summary

This study found that cluster headache patients, even during active attacks, show similar heart rate responses to oxygen level changes as healthy individuals. Therefore, significant heart rate fluctuations during cluster headaches are unlikely due to altered arterial oxygen saturation (SaO2).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Clinical features and prognostic analysis of transarterial chemoembolization combined with targeted immunotherapy in the treatment of patients with hepatitis B virus-related intermediate-and advanced-stage hepatocellular carcinoma with secondary cholestasis].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology·2024
Same author

[Effect of high-fat diet on respiratory function and diaphragm fibers in mice and its mitochondrial mechanism].

Zhonghua yi xue za zhi·2021
Same author

Protection against cold air and exercise-induced bronchoconstriction while on regular treatment with Oxis.

Respiratory medicine·2001
Same author

Familial mydriasis, cardiac arrhythmia, respiratory failure, muscular weakness and hypohidrosis.

Acta neurologica Scandinavica. Supplementum·2001
Same author

Do patients using long-term liquid oxygen differ from those on traditional treatment with oxygen concentrators and/or compressed gas cylinders? A comparison of two national registers.

Respiratory medicine·1998
Same author

SUNCT syndrome: duration, frequency, and temporal distribution of attacks.

Headache·1996

Area of Science:

  • Neurology
  • Cardiovascular Physiology

Background:

  • Cluster headache is a debilitating neurological disorder often accompanied by autonomic symptoms, including potential heart rate changes.
  • The role of arterial oxygen saturation (SaO2) in modulating heart rate during cluster headache episodes remains unclear.

Purpose of the Study:

  • To investigate the influence of varying arterial oxygen saturation (SaO2) levels on heart rate in cluster headache patients.
  • To compare the heart rate response to hypoxia and hyperoxia between cluster headache patients and healthy controls.

Main Methods:

  • Monitored pulse rate changes in 11 cluster headache patients (during cluster and remission phases) and 11 healthy controls.
  • Administered sequential 5-minute exposures to 100% oxygen (hyperoxia) and 12% oxygen (hypoxia) to induce SaO2 changes.

Related Experiment Videos

  • Recorded pulse rate every minute using a finger pulse oximeter throughout the procedure.

    • Main Results:

    • Cluster headache patients exhibited a slightly lower baseline pulse rate compared to controls, a trend maintained during the test.
    • Both hyperoxia and hypoxia induced significant decreases and increases in pulse rate, respectively, within each group.
    • No significant differences in heart rate response to SaO2 fluctuations were observed between cluster headache patients and healthy individuals.

    Conclusions:

    • Cluster headache patients demonstrate a heart rate response to changes in arterial oxygen saturation (SaO2) comparable to that of healthy individuals.
    • The significant heart rate variations sometimes observed during cluster headache attacks are unlikely to be a direct consequence of altered SaO2 levels.