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Antioxidant therapy in digestive diseases

T Yoshikawa1, Y Naito, M Kondo

  • 1First Department of Medicine, Kyoto Prefectural University of Medicine, Japan.

Journal of Nutritional Science and Vitaminology
|January 1, 1993
PubMed
Summary

Antioxidant therapy shows promise for digestive diseases by combating oxygen radical damage. Novel synthesized antioxidants like zinc-carnosine and ebselen offer new treatment avenues.

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Area of Science:

  • Gastroenterology and Hepatology
  • Oxidative Stress Research

Background:

  • Lipid peroxidation by oxygen radicals contributes to digestive diseases.
  • Gastric mucosal injury, intestinal damage, pancreatitis, and liver injury are linked to oxidative stress.

Purpose of the Study:

  • To review recent advances in antioxidant therapy for digestive diseases.
  • To highlight the role of antioxidants in preventing and treating these conditions.

Main Methods:

  • Literature review of studies on antioxidant therapy in digestive diseases.
  • Categorization of antioxidants into preventive and chain-breaking types.

Main Results:

  • Antioxidants are effective in treating various digestive diseases.
  • Lipid peroxidation is a key factor in disease pathogenesis.
  • Synthesized antioxidants show therapeutic potential.

Conclusions:

  • Antioxidant therapy is a viable strategy for digestive diseases.
  • Further research into novel antioxidants like zinc-carnosine and ebselen is warranted.

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