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Effect of dried ginger on human platelet function

A B Lumb1

  • 1Department of Anaesthetics, Harefield Hospital, Middlesex, UK.

Thrombosis and Haemostasis
|January 1, 1994
PubMed
Summary
This summary is machine-generated.

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This study found that 2g of dried ginger capsules did not affect platelet function in healthy males. Therefore, therapeutic doses of dried ginger are unlikely to cause bleeding issues.

Area of Science:

  • Pharmacology
  • Hemostasis
  • Natural Products

Background:

  • Ginger (Zingiber officinale) is widely used for its potential health benefits.
  • Some evidence suggests ginger may influence platelet activity and thromboxane synthetase.
  • The specific effects of dried ginger on platelet function require further investigation.

Purpose of the Study:

  • To investigate the effects of 2g of dried ginger on platelet function in healthy male volunteers.
  • To compare the impact of dried ginger with a placebo on various hemostatic parameters.

Main Methods:

  • Randomized, double-blind, placebo-controlled study design.
  • Eight healthy male volunteers participated.
  • Measurements included bleeding time, platelet count, thromboelastography, and whole blood platelet aggregometry.

Related Experiment Videos

  • Data collected at baseline, 3 hours, and 24 hours post-ingestion.

    • Main Results:

    • No significant differences were observed between the dried ginger group and the placebo group for any measured platelet function variables.
    • Bleeding time, platelet count, and aggregometry results remained unchanged.

    Conclusions:

    • Dried ginger, at a dose of 2g, does not appear to significantly affect platelet function or cause platelet dysfunction in healthy individuals.
    • The observed lack of effect may be due to the form (dried vs. fresh) or dosage of ginger.
    • Further research into dose-dependency and the form of ginger is warranted.