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Optimal drug and behavior therapy for treatment-refractory schizophrenic patients
R P Liberman1, T Van Putten, B D Marshall
1Camarillo-UCLA Research Center, Camarillo State Hospital, CA 93011-6022.
The American Journal of Psychiatry
|May 1, 1994
Abstract:
Thirteen treatment-refractory schizophrenic patients (10 men and three women) who were receiving more than 50 mg/day of haloperidol and who had been hospitalized for more than 1 year successfully tolerated a mean dose reduction of 63% with consequent improvement in psychopathology and side effects. The addition of intensive behavior therapy to the optimal dose of haloperidol yielded further improvements in functional behavior, such as self-care and social interaction.