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Updated: Aug 18, 2026

Cholesterol Efflux Assay
Published on: March 6, 2012
An international perspective on the cholesterol debate
W W Rosser1, W H Palmer, G Fowler
1Department of Family and Community Medicine, University of Toronto, Ontario, Canada.
Abstract:
For the past 5 years there has been an intensive debate and a number of conflicting guidelines suggesting what general practitioners (GPs) should do to screen and manage hyperlipidaemia. At a WONCA seminar in Vancouver in 1992, policies and guidelines from Canada, the UK, The Netherlands, New Zealand, Hong Kong and the USA were reviewed. It was concluded that cholesterol policy and guidelines tend to be influenced more by political and economic factors than by evidence of health benefit. International guidelines for cholesterol screening and management would be of minimal value, as GPs would have to interpret the epidemiological evidence of benefit from lipid screening and lipid lowering strategy in the context of each patient to arrive at optimum management.
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