[Mediastinitis secondary to esophageal ulceration after doxycillin]

Doxycillin is a tetracycline antibiotic widely used in outpatients, particularly for treating pelvic inflammatory disease, acne, and Rickettsial infections. Among the more common side effects is acute esophageal inflammation leading to ulceration and occasionally to perforation. We describe the clinical course of a 35-year-old woman with esophageal perforation secondary to the use of Doxycillin.