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Related Experiment Videos

[Keratoprosthesis with biocolonizable support]

J M Legeais1, G Renard, Y Pouliquen

  • 1Service d'Ophtalmologie, Hôtel-Dieu de Paris.

Journal Francais D'Ophtalmologie
|January 1, 1993
PubMed
Summary
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This study introduces a novel microporous fluorocarbon material for keratoprosthesis support, improving corneal stability and visual outcomes in patients with severe corneal disease.

Area of Science:

  • Ophthalmology
  • Biomaterials Science
  • Corneal Surgery

Context:

  • Current keratoprosthesis designs often face challenges with support stability and tissue integration.
  • Microporous materials offer potential for enhanced tissue integration and prosthesis fixation.

Purpose:

  • To evaluate the efficacy and safety of a new microporous fluorocarbon material as a support for keratoprosthesis.
  • To assess the impact of this novel material on visual acuity and anatomical stability.

Summary:

  • A keratoprosthesis utilizing a 9 mm microporous fluorocarbon flange (200 microns thick, 80 microns pore size) was implanted in 10 patients.
  • The fluorocarbon material demonstrated transparency and wettability post-implantation, promoting tissue stability and maintaining anterior chamber depth.

Related Experiment Videos

  • The optical core was made of polymethyl methacrylate (PMMA), 5 mm in diameter and 2.5 mm long.

    • Impact:

    • Achieved an average visual acuity of 20/60 in patients with indications including corneal burns, pseudopemphigus, trachoma, and edema.
    • Demonstrated good anatomical stability with only two cases of failure (dislocation and extrusion) in the initial follow-up period.
    • The 5 mm optical diameter provided a visual field of approximately 120 degrees.