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Updated: Aug 18, 2026

A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
[Intra- and postoperative cerebral blood flow in patients with subarachnoid hemorrhage from a ruptured aneurysm]
A Rossi1, M A Balestrero, F Cella
1Istituto di Anestesiologia e Rianimazione, Università degli Studi di Genova.
Abstract:
The CBF of eight patients, who underwent surgery for ruptured aneurysm, was monitored using the termodiffusion technique (TDF). The device employed in this investigation allowed a continuous monitoring in "real time" of the cortical flow. The purpose of the study was to detect disorders of autoregulation, which were evaluated with the autoregulation index (AI). Autoregulation was correlated with the neurological preoperative grading, the postoperative changes of CBF (Xe133 clearance) and the outcome. The results of this preliminary study showed a correlation between these parameters and stressed the value of CBF monitoring during surgery.
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