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Reliability of global impressions for assessing methylphenidate effects in children with attention-deficit
1Department of Psychiatry, Pennsylvania State University College of Medicine, Milton S. Hershey Medical Center, Hershey 17033.
Abstract:
Agreement between raters using global impressions to assess methylphenidate response was analyzed for children with Attention-Deficit Hyperactivity Disorder (ADHD) undergoing double-blind, placebo-controlled, crossover methylphenidate trials. Caregivers were more likely to disagree than agree when asked to rate the children as "better, same, or worse" during each day of the trial. Over-all agreement was 42.9%, only 9.6% above what would be expected based on chance alone. Further, none of the interrater reliability coefficients (Cohen's kappa) for the individual children were statistically significant.
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